Photochemical and Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime
نویسندگان
چکیده
منابع مشابه
Photochemical Rearrangement of 8- methyl Spiro [2.5] oct-7-en-4-one to 4-methyl Spiro [2.5] oct-4-en-6-one
Irradiation of &methyl spiro [2.5] oct-7-en-4-one through its singlet excited state resulted in the formation of 4-methyl spirO [2.5] oct-4-en -6-one. We have used the cyclopropyl moiety in the molecule as a probe to study the operating mechanism in the photochemistry of ?, ?-unsaturated compounds. The results showed that this photoisomerization probably occurs through a concerted process.
متن کاملphotochemical rearrangement of 8- methyl spiro [2.5] oct-7-en-4-one to 4-methyl spiro [2.5] oct-4-en-6-one
irradiation of &methyl; spiro [2.5] oct-7-en-4-one through its singlet excited state resulted in the formation of 4-methyl spiro [2.5] oct-4-en -6-one. we have used the cyclopropyl moiety in the molecule as a probe to study the operating mechanism in the photochemistry of ?, ?-unsaturated compounds. the results showed that this photoisomerization probably occurs through a concerted process.
متن کاملIdentification and Characterization of TRO19622 (Cholest-4-en-3- One, Oxime), a Novel Drug Candidate for Amyotrophic Lateral Sclerosis
Trophos, Parc Scientifique de Luminy case 931, 13288 Marseille cedex 9, France (T.B., B.B., M.M., C.D., P.G., P.D., E.S., D.M., M.D., R.M.P.) ; Washington University School of Medicine, Saint Louis, MO, USA (N.P.A., A.S.E., D.F.C.); U773 Inserm, Centre de Recherche Biologique Bichat Beaujeon (CRB3), Université Paris 7, Faculté de Médecine Bichat, 16 rue Henri Huchard, BP 416, 75018 Paris, Franc...
متن کاملCholest-5-en-7-one
In the deca-hydro-phenanthrenone ring system of the title compound, C(27)H(44)O, the two cyclo-hexane rings adopt chair conformations, whereas the cyclo-hexene ring adopts an envelope conformation. The cyclo-pentane ring is twisted. In the crystal structure, mol-ecules are stacked along the a axis, but no significant inter-molecular inter-actions are observed.
متن کاملIdentification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive death of cortical and spinal motor neurons, for which there is no effective treatment. Using a cell-based assay for compounds capable of preventing motor neuron cell death in vitro, a collection of approximately 40,000 low-molecular-weight compounds was screened to identify potential small-mol...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Serbian Chemical Society
سال: 2004
ISSN: 0352-5139,1820-7421
DOI: 10.2298/jsc0406413k